| abstract |
ABSTRACT OF THE DISCLOSURE: The invention is related to substituted N-aniline-4-chloro-3-sulphamoyl benzamides of general formula I (I) wherein R represents a hydrogen atom or methyl and R1 is methyl, ethyl, isopropyl, 2-hydroxyethyl or phenyl, and to a process for producing thereof consisting in acylation of substituted hydrazines of general formula II (II) with 4-chloro-3-sulphamoylbenzoyl chloride. Compounds of general formula I have diuretic and saliuretic activity and significant antihypertension effect. |