| abstract |
ABSTRACT There are described novel pharmaceutically active substances with valuable pharmacodynamic properties which exhibit especially pronounced anticonvulsive and anxiolytic activities and have only a low toxicity. These active substances correspond to the general formula I wherein A together with the two carbon atoms denoted as .alpha. and .beta. signifies the group (a) , (b) , (c) or (d) B signifies dimethylene, trimethylene or propenylene, R1 signifies hydrogen, halogen, trifluoromethyl, amino, nitro, cyano or lower alkyl and R2 signifies hydrogen, halogen, trifluoromethyl, amino, nitro, cyano, lower alkyl, lower alkoxy, lower alkylthio, lower alkyl-sulphinyl or lower alkylsulphonyl, and the carbon atom denoted as .gamma. has the (S)- or (R,S)-configuration, and can be used as medicaments in the form of pharmaceutical preparations. |