http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1185549-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a09ca043d7e596facff1f44b746e2f4d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fedff9cbce9d81a5aa8455226daa8801 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S424-825 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S424-83 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-522 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-099 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-095 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-01 |
filingDate | 1982-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1985-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_85e91490bbe48edb3541fa6d42880a0f |
publicationDate | 1985-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-1185549-A |
titleOfInvention | Method for the preparation of an improved mutant strain of bordetella bronchiseptica useful as a live attenuated vaccine for prophylaxis of b. bronchiseptica infection |
abstract | Abstract of the Disclosure: The invention provides a method for the preparation of a new mutant strain of Bordetella bronchiseptica having a plurality of hereditary chromosomal markers comprising at least temperature-sensitivity and urease negativity. In particular, the invention provides a phase I mutant strain of B. bronchiseptica having excellent immunity and high safety, which is useful for the preparation of a live attenuated vaccine for prophylaxis of B. bronchiseptica infection, and also a live attenuated vaccine prepared there-from. The mutant strain is obtained by applying a mutagen to a strain of B. bronchiseptica to provide a mutant strain having temperature sensitivity and urease negativity, culturing the mutant strain, picking up a cell growth with a relatively small colony, and repeating the procedure of picking up a cell and culture thereof to convert it to a phase I organism having capsular antigen and which is hemolytic. |
priorityDate | 1981-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 47.