| abstract |
PRECISION OF DISCLOSURE Process for the preparation of bicyclo-octane car-boxylics of formula: in which A represents a vinylene or dimethyl radical lene, q is 0 or 1, R is an alkyl radical which can carry an amino group, X represents - S - or - NH -, R1 is a hydrogen atom or a radical of formula: wherein R2 is hydroxy or alkoxy and R3 is hydrogen atom, an alkyl, cycloalkylalkyl or phenylalkyl which may contain a sulfur atom, process characterized in that a compound is reacted of general formula: in which A is the same as above and R 'represents hydroxy or lower alkoxy, with an acid derivative substituted carboxylic then, if necessary, a reductive alkylation reaction. These compounds are useful as medicaments, in particular antihypertensives. |