abstract |
Abstract Chiral 2-(2-benzyl-3-mercaptopropionylamino)-1-alkanol derivatives and chiral 2-(2-benzyl-3-mercapto-propionylamino)-4-methylthiobutyric acids are inhibitors of enkephalinese enzyme, reflecting their clinical utility as analgesics or anticonvulsant agents, or as therapy for disorders in which endogeneous enkephalin levels are below normal. |