http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1177400-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5712b4838bdb16ebbc41121239e165b9 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-43 |
| filingDate | 1983-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1984-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a426076fb9b7a5daae93620b5d942536 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0bff0e10688e64b6bb4618a0279d6a30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca03cce7f3db4d9828a3cdc6cc50ad9e |
| publicationDate | 1984-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-1177400-A |
| titleOfInvention | Derivatives of clavulanic acid, a process for their preparation and their use |
| abstract | A B S T R A C T Synergistic compositions comprising compounds of the formula (II): (II) or pharmaceutically acceptable salts or esters thereof wherein A is a hydrogen atom or an esterifying radical; X is an alkyl group of 1-12 carbon atoms optionally substituted by a hydroxy, amino, acylamino of C1-6 alkoxy group, which substituents are not on the carbon atom adjacent to the nitrogen atom; or a C5-7 cyclo-alkyl group; or a phenylalkyl group wherein the carbon atom content of the alkyl part is 1-6 and the phenyl part is optionally substituted with a fluorine, bromine, chlorine, C1-6 alkyl, or C1-6 alkoxy; with the proviso that when X represents an optionally substituted phenyl-alkyl group and A represents C1-3 alkyl, then the -CO2A group is attached to the alkyl part of the phenyl-alkyl group; in admixture with penicillins and/or cephalosporins in pharmaceutically acceptable form. These compositions have enhanced activity as .beta.-lactamase inhibitors and antibacterial agents. |
| priorityDate | 1979-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 164.