abstract |
ABSTRACT The present invention relates to new dibenz-oxazonine, dibenz-oxazecine or dibenzo-oxaazacyclo-undecane derivatives and corresponding thia- and aza derivatives thereof, of the general formula I: I or a pharmaceutically acceptable acid addition salt or nitrogen oxide thereof, in which X represents oxygen, sulphur or the group NR5, R5 is hydrogen or alkyl (1-4 C), R1, R2, R3, R4 each represent hydrogen, hydroxy, halogen, cyano, alkyl, alkyl, aralkoxy, alkylthio, methylenedioxy, CF3, NO2, NH2, hydroxy-alkyl or an acyloxy group, R represents hydrogen, alkyl, alkenyl or aralkyl, hydroxyalkyl or acyloxy-alkyl and n represents the number 0, 1 or 2, having valuable C.N.S. properties. |