http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1173037-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5deddb47ccaab1d4da2aacc344dd8717 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-58 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-72 |
| filingDate | 1981-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1984-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d3312ab4b790476fa253a71f597c7fbb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_005ae658e50208f3fedc5a681b8983a9 |
| publicationDate | 1984-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-1173037-A |
| titleOfInvention | Piperidino ureas as antidepressants |
| abstract | ABSTRACT The invention concerns the preparation of compounds of formula (I) and acid addition and quaternary ammonium salts thereof, wherein the dotted line represents an optional bond, Ar represents a ring system of formula (Ia) in which Q is 0, 5, -CR7=CR8-, -N=CR8- and -N=N-; R4, R5 and R6, and R7 and R8 when present, each represent hydrogen or a substituent selected from lower alkyl, lower alkenyl, lower alkoxy, NO2, NH2, haloloweralkyl, hydroxyloweralkyl, aminoloweralkyl, substituted amino, loweralkoxycarbonyl, cyano, CONH2 and hydroxy; and additionally either R4 and R5 when adjacent or R6 and R8 when adjacent, together with the carbon atoms to which they are attached also represent a fused five or six membered carbocylic or heterocyclic ring optionally carrying one or more substituents as defined above; R is an optionally substituted aryl or heteroaryl radical or a cycloalkyl radical containing 5 to 7 carbon atoms; R1, R2, R3 and R9 are each hydrogen or a lower alkyl group; n is 0 or 1; X is =O, =S or =NH; Y is -O- or a direct bond and Z is -CO- or -CH2-, with the proviso that uhen Ar is unsubstituted phenyl and R9 is hydrogen then Y is -O-. The compounds of formula I exhibit psychotropic activity and are useful as antidepressants. |
| priorityDate | 1980-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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