abstract |
Abstract: The synthesis of C-4 alkyl homologs of racemic (1RS, 4SR,5RS)-4-(4,8-dimethyl-5-hydroxy-7-nonenyl)-4-methyl-3,8-dioxabicyclo[3.2.1]octane-1-acetic acid and the corresponding (1RS,4RS,SRS) - derivative is described. The dioxabicylo[3.2.1]octanes are useful as contragestational agents. |