http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1168580-A

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classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-102
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-564
filingDate 1981-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1984-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e6a6d6ad962fbea9cf313cb93e7a50b
publicationDate 1984-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-1168580-A
titleOfInvention Immunological reagent for the detection of tubes of the rheumatoid factor in a biological specimen and process for preparing this novel reagent
abstract ABSTRACT NOVEL IMMUNOLOGICAL REAGENT FOR THE DETECTION OF THE RHEUMATOID FACTOR IN A BIOLOGICAL SPECIMEN AND PROCESS FOR PREPARING THIS NOVEL REAGENT. The invention relates to a reagent for the detection of rheumatoid factor in tests in tubes or microplates. The reagent contains a complex formed from red blood cells and from antibodies soluble with respect to these red blood cells, and immunologically fixed to the latter, said reagent being both stable and capable in given dilution intervals to give rise to hemagglutination only subject to contacting it with detectable concentrations of rheumatoid factor. The invention also relates to a process for making said reagent which comprises subjecting red cells and the antibodies to be fixed thereon to successive treatments with distinct aldehydes or tanning agents, as well as with proteinic substances, such as albumin, having dispersive properties. Finally the invention also provides a process for detecting the presence of rheumatoid fractor in biological specimen which comprises contacting the latter with said reagent, whereby the response is positive or negative depending upon whether pattern hemagglutination or sedimentation of the cells of the complex is observed.
priorityDate 1980-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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