http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1165315-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c902faf6ae746c51fc8010672fc22894 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7064 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L25-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L25-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-445 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-452 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J3-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H5-08 |
| filingDate | 1980-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1984-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7fd7ea9304db9c35ccd83838e429afd8 |
| publicationDate | 1984-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-1165315-A |
| titleOfInvention | Analogs of lincomycin and clindamycin |
| abstract | ABSTRACT OF THE DISCLOSURE Novel useful analogs of the well known antibiotics lincomycin and clindamycin. These analogs are prepared by condensing a cyclic acid with a sugar amine and are repre-sented by the general formula: wherein R1, which can be singly or multiply substituted in the 2, 3, 4, 5, 6, 7, 8 or 9 position of the ring not already substituted by R2, is hydrogen, alkyl and substituted alkyl, wherein the alkyl portion is from 1 to 8 carbon atoms, and isomeric forms thereof, cycloalkyl and substituted cyclo-alkyl, substituted oxygen, substituted nitrogen, halogen, phenyl and substituted phenyl or -(CH2)m-OH, -(CH2)m-NR4R5, and isomeric forms thereof, wherein m is an integer of from 1 to 8, and R4 and R5 are hydrogen or alkyl of from 1 to 8 carbon atoms and isomeric forms thereof; wherein R2, which can be singly substituted in any position of the ring not already substituted by R1, is: -?-X and X is the amino function of 7(R)-hydroxy-methyl l-thio-.alpha.-lincosaminide, 7(S)-hydroxy-methyl l-thio-.alpha.-lincosaminide, 7(S)-halo-methyl l-thio-.alpha.-lincosaminide, 7(R)-halo-methyl l-thio-.alpha.-lincosaminide, 7(S)-methoxy-methyl l-thio-.alpha.-linco-saminide, 7-deoxy-7(S)-(methylthio)-methyl l-thio-.alpha.-linco-saminide, 7-deoxy-7(S)-(2-hydroxyethylthio)-methyl l-thio-.alpha.-lincosaminide or 7-deoxy-7(S)-(3-hydroxypropylthio)-methyl l-thio-.alpha.-lincosaminide; wherein R3 is hydrogen, methyl 7 ethyl or C2H5OH; and wherein n is an integer of from 1 to 4. |
| priorityDate | 1979-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 194.