http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1165235-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a09ca043d7e596facff1f44b746e2f4d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1374dd16777534b65ad4422333245af8 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-831 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39591 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 |
| filingDate | 1980-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1984-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_83fa90e31f5b1b504864046a1f25923b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38ba6321b467ba324c4d5978da3e181d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_792bb57d2de1fe843a547d3e149a7ff8 |
| publicationDate | 1984-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-1165235-A |
| titleOfInvention | Immunoglobulin composition having a high monomer content, and process for production thereof |
| abstract | Abstract of the Disclosure An immunoglobulin composition comprising an immuno-globulin, and as an aggregation preventing agent or an aggregate dissociating agent for the immunoglobulin, about 1 to about 600% by weight, based on the weight of the immuno-globulin, of a water-soluble acid additive salt of a basic nitrogen containing organic compound containing one or more basic nitrogen atoms in the molecule and optionally carboxyl groups in smaller number than the basic nitrogen atoms and having a pKb at 25°C of not more than 7; and a method for producing an immunoglobulin composition having a high monomer content, which comprises contacting an immunoglobulin in aqueous solution with about 1 to about 600% by weight, based on the weight of the immunoglobulin, of a water-soluble acid addition salt thereby to prevent aggregation of the monomer of the immunoglobulin, and when the immunoglobulin contains aggregated molecules, dissociating the aggregated molecules into monomers, and thereafter, if desired lyophilizing the resulting product. |
| priorityDate | 1979-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 56.