http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1163196-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3a5173a7d063a9f70ca7b5e86fc23863 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2866 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-60 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-60 |
| filingDate | 1981-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1984-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3e55ce8f5b6c44a348573ad747c8496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad7452fe3895d5dc1e0530dfbb3d037e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c612ba1b2c122005c38c883d6bdec5b |
| publicationDate | 1984-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-1163196-A |
| titleOfInvention | Aqueous spray-coated asa tablet |
| abstract | ABSTRACT OF THE DISCLOSURE A method for preparing an easily-swallowed, powder-free, gastric-disintegrable and thinly coated ASA tablet, which does not have the characteristic ASA taste, does not produce the esophageal discomfort of an uncoated ASA tablet and does not disintegrate in the stomach materially slower than the uncoated ASA tablet, which comprises aqueous spray-coating hydroxypropyl methylcellulose onto all exterior surfaces of an ASA tablet, the amount of hydroxypropyl methylcellulose being between 0.5 and 2.0 parts by weight per 100 parts by weight of the ASA tablet. An aqueous solution of 2% to 15% by weight of hydroxypropyl methylcellulose and about 15% to 25% w/w of a plasticizer based on hydroxypropyl methylcellulose is sprayed onto uncoated ASA tablets in a slowly rotating baffled pan in a chamber equipped to measure and control both inlet and outlet air flow rates and both inlet and outlet air temperatures, said air flow rates and temperatures being sufficient to insure rapid evaporation of the water and to provide an evenly-applied thin coating of hydroxypropyl methylcellulose onto the uncoated tablets without causing their decomposition and/or physical disintegration. Preferred pan-rotation speeds, inlet and outlet air flow rates and temperatures are given. Other aspects of the invention are said thinly-coated tablets and said coated tablets when produced by said aqueous spray-coating method. |
| priorityDate | 1980-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.