http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1159840-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bbbb31e7315b8accd6544acf506c2d88 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D313-08 |
| filingDate | 1982-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1984-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b0ba01389c63578655fcc3fe1a58894 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3dbb68b9cabd0b1e0d2a9973602a4c63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_800f980728cf67ffc6b38eda83f02b1c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f89e071efbd7f5fc9d061ba27b38a9b0 |
| publicationDate | 1984-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-1159840-A |
| titleOfInvention | 2,3,4,5-tetrahydro-1-benzoxepin-3,5-dione derivatives |
| abstract | ABSTRACT OF THE DISCLOSURE The present invention provides 2,3,4,5-tetrahydro-1-benzoxepin-3,5-dione derivatives of the following Formula II II wherein R3 and R4 independently of one another are halogen, C1-C4 alkyl, C1-C4 alkoxy, C1-C4 alkylthio or one of R3 and R4 are halogen, C1-C4 alkyl, C1-C4 alkoxy, C1-C4 alkylthio, trifluoro-methyl or nitro and the other is hydrogen, with the proviso that R3 is not bromine when R4 is methyl, which are intermediates in the preparation of 3-amino-1-benzoxepin-5(2H)-one derivatives corresponding to the Formula I: I wherein: R1 and R2 independently of one another are hydrogen, C1-C5 alkyl, C1-C5 alkyl substituted with a terminal phenyl, or a phenyl containing one or two halogens, methyl or methoxy groups, a 3,4-methylenedioxy or a 3,4-ethylenedioxy group, C2-C5 alkyl, C2-C5 alkyl substituted with terminal hydroxy or methoxy or C3-C4 alkenyl; or one of R1 and R2 are hydrogen or a C1-C5 alkyl and the other is a C2-C5 alkyl substituted with a terminal NR5R6; R5 and R6 independently of one another are hydrogen or C1-C5 alkyl; or R5 and R6 are together a 5 to 7 member ring, or R5 and R6 are together a 5 to 7 member ring having heterogeneous oxygen, sulfur or nitrogen; R1 and R2 are together a 5 to 7 member ring, or R1 and R2 are together a 5 to 7 member ring having heterogeneous oxy-gen, sulfur or NR7; R7 is hydrogen, methyl, benzyl or phenyl; and R3 and R4 are as above; and pharmaceutically acceptable acid addi-tion salts thereof, which are useful in the treatment of spasms of the stomach-intestinal tract. |
| priorityDate | 1979-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 150.