http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1159450-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ca2e4410855da087e11bf3eea8933fa |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-045 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-56 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-56 |
| filingDate | 1980-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1983-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_467c40b53dbcf38be417c301e6415da7 |
| publicationDate | 1983-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-1159450-A |
| titleOfInvention | Process for the preparation of derivatives of cyclic peptide nuclei |
| abstract | Abstract of the Disclosure The invention disclosed herein provides compounds of the formula III wherein R1 is H or OH; and when R1 is H, R2 is H and R3 and R4 are both H or both OH, and when R1- is OH, R2 is H, R3 is OH or C1-C6 alkyloxy and R4 is OH, or R2 is -CO-NH2 and R3 and R4 are both OH, and wherein R5 is a group of the formula: (a) (b) ; or ( C ) wherein A is divalent oxygen, sulfur, sulfinyl, or sulfonyl; A1 is divalent oxygen, sulfur, sulfinyl, sulfonyl or -NH-; X is hydrogen, chloro, bromo, iodo, nitro, C1-C3 alkyl, hydroxy, C1-C3 alkoxy, mercapto, C1-C3 alkylthio, carbamyl or C1-C3 alkylcarbamyl; X1 is chloro, bromo or iodo; R6 is hydrogen C1-C18 alkyl or C2-C18 alkenyl; W is C1-C10 alkylene or C2-C10 alkenylene; m, n and p are 0 or 1, but if m = 0, n must = 0; provided: that the sum of the carbon atoms in the R6 and W groups must be greater than 4 but cannot exceed 21; that when X is mercapto, A and A1 cannot be sulfinyl or sulfonyl and that when A and A1 are sulfinyl or sulfonyl, they must be in equal oxidation states. These compounds have antifungal activity. Also provided by the invention is a process for preparing such compounds. |
| priorityDate | 1979-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 156.