http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1156145-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d202e9e866984fe229f6facc38f1d740 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-785 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 |
| filingDate | 1980-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1983-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90e002af93d40263cccbc5ad2bd19354 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_22cc4520ab862b679c96f262fa7e520a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_23679847f9d3262124f17e336a886e5b |
| publicationDate | 1983-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-1156145-A |
| titleOfInvention | Pharmaceutical composition comprising modified polyriboinosinic-polyribocytidylic acid, for induction of interferon in primates |
| abstract | 16336IA TITLE OF THE INVENTION Pharmaceutical Composition Comprising Modified Polyriboinosinic-Polyribocytidylic Acid, for Induction of Interferon in Primates. ABSTRACT OF THE INVENTION A complex of polyriboinosinic-polyribocytidylic acid (poly I:C) with poly-L-lysine hydrobromide ([lysine.HBr]n) having a defined molecular weight is prepared which is about 5-15 times as resistant to hydrolysis by pancreatic ribonuclease as the parent poly I:C. A pharmaceutical solution, con-taining a relatively high concentration of the complex, prepared as described, induces significant antiviral levels of serum interferon in monkeys under conditions in which poly I:C itself induces little or no interferon. An important feature of this invention is that the product is a soluble material requiring no special solubilizing agent, thereby facilitating the preparation of solutions having the desired concentration. The product will hereinafter be designated as poly I:C/poly-L-lysine. |
| priorityDate | 1979-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.