http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1154442-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2de3beee83d9c19278da409b72c777a8 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C405-0041 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C405-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C405-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-557 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-52 |
filingDate | 1980-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1983-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59b72f1da74dc80480bf5c440b9dc994 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8eeae1b777201c1ca98d195cb4e84ad1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34628049256aaab225a219993e040d6d |
publicationDate | 1983-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-1154442-A |
titleOfInvention | 6,9-nitrilo-prostaglandin analogues |
abstract | A B S T R A C T 6 9 -NITRILO-PROSTAGLANDIN ANALOGUES" Prostaglandin I2 analogues of the general formula: II [wherein R1 represents a hydrogen atom, an alkyl group containing from 1 to 12 carbon atoms, an aralkyl group containing from 7 to 13 carbon atoms, a cycloalkyl group containing from 4 to 7 carbon atoms unsubstituted or substituted by at least one alkyl group containing from 1 to 4 carbon atoms, a phenyl group unsubstituted or substituted by at least one halogen atom, trifluoromethyl or phenyl group, or by at least one alkyl, alkoxy or alkylthio group containing from 1 to 4 carbon atoms, or represents a group , or , in which m represents an integer of 1 to 12, n represents an integer of 2 to 12, R6 , R8 and R9 , which may be the same or different, each represent an alkyl group containing from 1 to 4 carbon atoms, and R7 represents a hydrogen atom or an alkyl group containing from 1 to 4 carbon atoms, R2 represents a hydrogen atom, or a methyl or ethyl group, R3 represents an alkyl group containing from 1 to 4 carbon atoms, R4 represents a hydrogen atom, or an alkyl group containing from 1 to 4 carbon atoms, R5 represents an alkyl group containing from 1 to 10 carbon atoms, Y represents ethylene or trans-vinylene, the hydroxy group attached to the C-ll carbon atom is in a-configuration, and the wavy line attached to the C-15 carbon atom is in .alpha.- or .beta.-configuration or a mixture thereof]and non-toxic acid addition salts thereof and, when Rl represents a hydrogen atom, non-toxic salts thereof are new compounds possessing pharmacological properties typical of the prostaglandins. |
priorityDate | 1979-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 122.