http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1154021-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ba090c867801ab7bccb082f1b694ad25 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-425 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12 |
| filingDate | 1980-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1983-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b47027c320dedcc996738089bfe5d53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46272f8fff9904defdef2781adfb365e |
| publicationDate | 1983-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-1154021-A |
| titleOfInvention | Guanidine compounds, process for preparing them and compositions containing them |
| abstract | ABSTRACT OF THE DISCLOSURE The present invention provides compounds of formula (I):- (I) and pharmaceutically acceptable salts thereof, which have histamine H2-antagonist activity. In formula (I) Z is sulphur or methylene and R1 is hydrogen, C1-4 alkyl, optionally substituted phenyl or phenyl (C1-4 alkyl) (the substituents being one or more C1-4 alkyl, or C1-4 alkoxy groups or halogen atoms or a methylenedioxy group), or optionally substituted furanyl-, thienyl-, or pyridyl-(C1-4 alkyl) (the substituents being one or more C1-4 alkyl or C1-4 alkoxy groups); and R2 is hydrogen, C1-4 alkyl or benzyl. One particular compound of formula (I) is 2-[2-(2-guanidino-4-thiazolylmethylthio)ethylamino -3-nitro pyrrole. |
| priorityDate | 1979-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 61.