http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1152508-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a900e1bcff6702df57be0c71d1180ff6 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-13 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-06 |
filingDate | 1980-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1983-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9a711fd511bfd789c87d3a8ef41c011 |
publicationDate | 1983-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-1152508-A |
titleOfInvention | Phenylsulphonamide derivatives, a process for their preparation and their use as medicines |
abstract | ABSTRACT Pharmaceutical compositions which comprise a compound of the formula (I): (I) or a salt thereof wherein NR2 represents a piperodyl, pyrrolidyl, morpholino or N-methyl-piperazyl group any of which may substituted by one or two methyl groups, R1 represents fluorine, chlorine bromine, iodine, lower alkoxyl, hydroxyl, acetoxyl, nitro, cyano, amino, dimethylamino, lower alkyl, trifluoromethyl, methylthio, ethylthio, methoxycarbonyl, ethoxycarbonyl, acetamido or carboxamido; R2 represents hydrogen, flurorine. chlorine, bromine, iodine, lower alkoxyl, hydroxyl, lower alkyl, R3 represents hydrogen, chlorine or lower alkyl, or R1 and R2 when on adjacent carbon atoms may togehter represent a polymethylene group containing from 3 to 5 carbon atoms: and n is 2, 3 or 4: and a pharmaceutically acceptable carrier. compounds of formula (I) except those wherein R1 is a 2-methoxyl group, and 2,4-dimethyl-1-[2-(4-bromophenylsulphonamido)ethyl]pyrrolidine and 2.4-dimethyl-1-[2-(4-bromophenylsulphonamido)ethyl]pyrrolidine, a process for the preparation of compounds of the formula (I) and 2,4-dimethyl-1-[2-(4-bromophenylsulphonamido)ethyl]-pyrrolidine and 2,4-dimethyl-1[2-(4-iodophenylsulphonamido) ethyl]pyrrolidine as antiarrhythymic agents. |
priorityDate | 1979-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 138.