| abstract |
- ABSTRACT -The compounds of formula (II): (II) in which R1 is a hydrogen, fluorine, chlorine or bromine atom or a hydroxyl, hydroxymethyl, methyl, methoxyl, amino, formamido, acetamido, methyl-sulphonylamido, nitro, benzyloxy, methylsulphonyl-methyl, ureido, trifluoromethyl or p-methoxy-benzylamino group; R2 is a hydrogen, fluorine, chlorine or bromine atom or a hydroxyl group; R3 18 a hydrogen, chlorine or bromine atom or a hydroxyl group, R4 is an alkyl group of 1 to 10 carbon atoms substituted by a hydroxyl, lower alkoxyl, oxo, lower acyloxy or OCH2CO2H group or lower alkyl ester thereof; R5 is a hydrogen, chlorine or fluorine atom or a methyl, methoxy or hydroxyl group or a carboxylic acid group or a salt, ester or amide thereof; R6 is a hydrogen atom or a methyl, ethyl or propyl group; R7 is a hydrogen atom or a methyl, ethyl or propyl group; X is an oxygen atom or a bond; and Y is an alkylene group of up to 6 carbon atoms or a bond, have been found to possess anti-obesity and/or anti-hyper-glycaemic activity. |