| abstract |
PRECISION OF DISCLOSURE The subject of the present invention is new cephalosporins of general formula (I) (I) in which n = 0 or 1, R1 is a radical of general formula (II) (II) (in which R4 is a protective radical and R5 is an atom hydrogen, an alkyl, vinyl, cyanomethyl radical or a protective radical), or R1 is a protective radical, and R2 is a protective radical or a radical which can be eliminated by way enzymatic, or else R1 is a variously sub- acyl radical stitué and R2 is a protective radical. The formula product general (I) is in the form of 3-oxoethyl-2-bicyclooctene or -3 when n = 0, and in the form of oxoethyl-3 bicyclooctene-2 when n = 1. The invention also relates to the method of preparation of the products of general formula I. These new products are useful as intermediates for preparation of pharmaceutically active cephalosporins. |