http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1148146-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3e9445e5e3626f36e932c6451a928250 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S930-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-6555 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-655 |
| filingDate | 1980-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1983-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f2c1b162b77881420e9c3fe69cb68b9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a593c42348fee7d40157b7e69951a39a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_18db57a33f5b62e8eae984590a771e05 |
| publicationDate | 1983-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-1148146-A |
| titleOfInvention | Cyclopeptides and pharmaceutical preparations thereof and also processes for their manufacture |
| abstract | Case 4-12421/1+2/= New cyclopeptides and pharmaceutical preparations thereof and also processes for their manufacture Abstract The somatostatin-analogous cyclic octapeptides according to the invention of the general formula (I) in which trp represents L-Trp or D-Trp, in which the benzene ring may be substituted by a halogen atom, and Gaba(Ar) represents the residue of a .gamma.-amino-butyric acid substituted by a cyclic hydrocarbyl radical, and their acid addition salts and complexes are distin-guished by a strong inhibition of the insulin and glucagon secretion of the pancreas and are therefore therapeutically acceptable, preferably in the form of phanmaceutical preparations, in similar indications to those of somatostatin, especially as anti-diabetics. The compounds are manufactured by conventional processes of peptide synthesis, especially by liberation from corresponding protected intermediates after intramolecular cyclisation of a corresponding linear octapeptide. |
| priorityDate | 1979-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 371.