http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1147325-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5712b4838bdb16ebbc41121239e165b9 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D499-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D499-56 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-00 |
| filingDate | 1980-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1983-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac5374cdee283a0bea50423343c6f875 |
| publicationDate | 1983-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-1147325-A |
| titleOfInvention | Process for the preparation of penam derivatives |
| abstract | ABSTRACT A process for the preparation of a penam derivative of formula (I): (I) wherein R is phenyl, p-hydroxyphenyl, p-(C1-6)-alkyl-carbonyloxyphenyl or 2- or 3-thienyl, R1 is hydrogen, or a pharmaceutically acceptable salt-forming ion or ester-forming radical, and R2 represents hydrogen or a pharmaceutically acceptable salt-forming ion or in vivo hydrolysable ester-forming radical; which process comprises reacting a suitably protected 6,.alpha. arylthio derivative with methanol in the presence of either:(a) silver, thallium or mercuric ions; or (b) chlorine and a base; and thereafter if necessary removing the protecting groups, and converting the product to a pharmaceutically acceptable salt or ester thereof. |
| priorityDate | 1979-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 72.