| abstract |
ABSTRACT The invention relates to 8-arylalkyl-3-phenyl-3-nortropanols of the general formula: (wherein Ar represents a group of formula R1, , or , in which R1 is hydrogen, fluorine, bromine, methyl or methoxy; X is a F, -O-, -S- or -NH- group; and R is hydrogen, 4-fluorine, 4-chlorine, 4-trifluoromethyl, 3-trifluoromethyl, 3-trifluoromethyl-4-chlorine, 4-methyl or 4-methoxy), and acid addition salts thereof. The compounds I can be obtained by reacting a 3-phenyl-3-nortropanol or the general formula: II with an alkylating agent of the general formula Ar-X-CH2-CH2-CH2-y III The compounds exhibit a C.N.S.-sedating action and can be used as neuroleptics. |