http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1139697-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d669af06cb2abbcd6823699582a97002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aac141a3051e128a54ab3843e7aa47e2 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-813 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P13-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P13-06 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-06 |
filingDate | 1980-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1983-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d87de3389d2f4aba1f465250e641109 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4995c0e254bbdc0a51d597df3ce58d7d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a738e36a6ff83b8b8ce126cb194ee092 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1645059e08497709199b61a7e3bf7ced http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0cc0dccf78cf02f86b482ca5fceae6d7 |
publicationDate | 1983-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-1139697-A |
titleOfInvention | PROCESS FOR THE CONTINUOUS ENZYMATIC CONVERSION OF WATER-SOLUBLE AND .alpha.-KETOCARBOXYLIC ACIDS INTO THE CORRESPONDING AMINO ACIDS |
abstract | ABSTRACT OF THE DISCLOSURE Water-soluble .alpha.-ketocarboxylic acids are continuously converted into the corresponding amino acids in a diaphragm reactor. The conversion is carried out in the presence of a substrate-specific dehydrogenase, ammonium ions and, as the coenzyme, nicotinamide-adenine dinucleotide (NAD+/NADH), which had been increased in the molecular weight by linkage to a water-soluble polymer. At the same time NADH is continuously regener-ated from NAD+ in the presence of a formate dehydrogenase and formate ions. The diaphragm must have an average pore diameter of 1 to 3 nm. From 0.1 to 10 mmoles/litre of NAD+/NADH linked to a poly-oxyethylene having an average molecular weight between 500 and 50,000 are used as the coenzyme. A substrate flow containing 50 to 100% of the maximally soluble quantity (but not more than 200 mmoles per litre) of the .alpha.-ketocarboxylic acid to be reacted, in the form of a water-soluble salt, a quantity of ammonium ions approximately equimolar to the quantity of substrate and 100 to 6,000 mmoles/litre of a formate is continuously fed to the reactor. A differential pressure of 0.1 to 15 bars is maintained across the diaphragm. A filtrate flow containing the amino acid formed is continuously drawn off behind the diaphragm. |
priorityDate | 1979-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 91.