http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1139661-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1271b9bfbefd8c8af27be811851415d6 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6421 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-64 |
| filingDate | 1980-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1983-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bda6ff26d0d19530889791731b571754 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a1f12cda0bfce344ec97dbc0ce347fb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e683706c00993179d2377a688c2e324 |
| publicationDate | 1983-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-1139661-A |
| titleOfInvention | Plasminogen-activating substance and the preparation and use of such substance |
| abstract | ABSTRACT OF THE DISCLOSURE A new type of plasminogen-activating substance is extracted from the bile of hogs. That substance is characterized by: (A) a molecular weight of 80,000 ? 10,000; (B) an isoelectric point of 7.1; (C) an ultraviolet absorption spectrum showing a peak (.lambda. max) at a wave length of 278 nm; (D) a fibrinolysis activity such that a Ca-added standard fibrin plate is lysed but a heated fibrin plate is not lysed; (E) such a high thermal stability that heating at a temperature of 80°C. for 10 min-utes causes the plasminogen-activating activity to be decreased to an extent corresponding to 50% of the original activity and heating at a temperature of 60°C. for 30 minutes causes the plasminogen-activating activity to be decreased to an extent corresponding to from 30 to 40% of the original activity; (F) a solubility in a salin solution and an insolu-bility in water-soluble organic solvents; and (G) a synthetic substrate-lysis activity such that Glutaryl-Gly-Arg-MCA and Pro-Phe-Arg-MCA are only marginally hydrolysed. Such substance can be used as an essential component of a therapeutic medicine for thrombosis. |
| priorityDate | 1979-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 97.