| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3ae66cc8b2f2f3f1513168c123a21925 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-6093
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-806 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-645
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-62 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-095 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-10 |
| filingDate |
1980-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1982-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86a8c8738fd61fe6efa1c71ac00ca214 |
| publicationDate |
1982-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-1138438-A |
| titleOfInvention |
Immunochemical conjugates: method and composition |
| abstract |
Abstract of the Disclosure Techniques for preparing stable conjugates of protein-?-GL which can then be isolated in pure form are disclosed, using hen egg ovalbumin (OVA) as a prototype protein, and conjugation and purification methods are described which involve 1) application of a coupling method employing m-maleimidobenzoyl-N-hydroxysuccinimide ester (MBS) as the coupling reagent, and 2) introduction of biotin moieties into ?-GL molecules to allow application of avidin-biotin system for affinity chromatographic purification of conjugates. These methods are applicable to the preparation of ?-GL conjugates of insulin and Ragweed Antigen E and are of general applicability. |
| priorityDate |
1979-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |