http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1135338-A

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D59-30
filingDate 1979-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1982-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76cff4da14eb292f0174f5c58b6cd44c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01f3b7c569fafd14cc44a9473c787f22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_40fe15c93cf94785826ca51797abb77f
publicationDate 1982-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-1135338-A
titleOfInvention Combination apparatus and method for chromatographic separation and quantitative analysis of multiple ionic species
abstract COMBINATION APPARATUS AND METHOD FOR CHROMATOGRAPHIC SEPARATION AND QUANTITATIVE ANALYSIS OF MULTIPLE IONIC SPECIES Apparatus and method for chromatographic separation and quantitation of different ions of like charges in a sample, e.g., cations or anions. Referring to anion separation, the sample is directed to a first chromatographic column of the ion exclusion type in which the weak acids (e.g., carboxylic acids) and their salts are resolved and separated from a fraction of strong acids (e.g., mineral acids) due to Donnan exclusion. The resolved weak acids are passed to a conductivity cell for quantitative detection. The strong acids are directed to anion exchange bed with a highly ionized developing reagent and eluted in resolved form. The effluent is passed to a suppressor ion exchange bed wherein the developing reagent is converted to a weakly ionized form without destroying the anion separation. Then, a fraction of the strong acids is detected with the same or a different conductivity cell. Prior to separation, the strong acids are preferably directed through a concentrator column formed of ion exchange resin in which they are retained but not resolved while the remaining solution is removed. Thereafter, the developing agent used for separation of the strong anion is passed through the concentrator column to remove the anions for resolution. The same technique can be employed for cations.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114689830-A
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type http://data.epo.org/linked-data/def/patent/Publication

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