http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1134357-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a157f5faa443ba5bb3367371f1e2a6c7 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C405-00 |
| filingDate | 1978-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1982-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c86c66d0cc872f90cada2c441c4f325b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d93a7bbab38c5291f3ba840ee6daab8a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_beb9724c748d03e15cc1dcd2a7344bef http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_348f418053d4fb8a8be0b29727c5301f |
| publicationDate | 1982-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-1134357-A |
| titleOfInvention | 17-AZA-PGF IN2.alpha. XX DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME |
| abstract | ABSTRACT OF THE DISCLOSURE This invention relates to novel prostaglandin F2.alpha.(PGF2.alpha.) deriva-tives having the general formula (XII) (XII) or a racemate thereof, wherein R1 is hydrogen, lower alkanoyl, trihaloalkanoyl, optionally substituted benzoyl, lower alkoxycarbonyl, lower trihaloalkoxy-carbonyl, or optionally substituted phenoxycarbonyl or benzyloxycarbonyl; R2 is hydrogen or alkyl of one to 4 carbon atom(s), R4 is hydrogen or a protect-ing group; Q is hydrogen, alkyl of one to 4 carbon atom(s) or a pharmaceuti-cally acceptable non-toxic cation. This invention also relates to the racemate consisting of one of the optically active isomers and its mirror image. A process or the preparation of the above compounds is also disclosed. The compounds according to the invention possess valuable prostaglandin-like pharmaceutical activity, are much more effective than natural PGP2.alpha. and show definite .alpha.-adrenergic stimulating activity. |
| priorityDate | 1978-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 113.