abstract |
ABSTRACT OF THE DISCLOSURE New phenyl alkanoic acids are provided of the formula: wherein R1 is aralkyl containing up to 10 carbon atoms in the aryl moiety and 1 to 4 carbon atoms in the alkyl moiety or phenyl substituted with halogen, amino, lower alkyl, lower alkoxy or carboxy(lower)alkyl, R2 is hydrogen or halogen, R3 is amino, mono-alkylamino, di-alkylamino or mesylamino, R4 is a group of the formula CnH2n in which n is an integer of 1 or 2, and A is oxy, thio, sulfinyl, sulfonyl or imino, and the derivatives at the carboxy group, and pharmaceutically acceptable salts thereof; the new acids have anti-inflammatory, analgesic and antipyretic activities. |