http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1124729-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_73ee0bacab5a7576a6a3244747f6ea99 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e7c22980d25eb1d159f269bf4aa2c03c |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D285-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D285-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-433 |
filingDate | 1979-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1982-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d125799dbc7d037712f2ff519429909e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c68a02ca08ef23960f15f1632b77a32 |
publicationDate | 1982-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-1124729-A |
titleOfInvention | Antisecretory thiadiazole derivatives, processes for their manufacture and pharmaceutical compositions containing them |
abstract | ABSTRACT OF THE INVENTION The invention relates to a thiadiazole derivative of the formula I: in which Y is O, S, CH2, 50 or a direct bond; m is 0 to 4 and n is 1 to 4 provided that when Y is S, O or SO m is 1 to 4, and when Y is O or SO n is 2 to 4; R is H or (Cl-lO)alkyl; A is 3,4-dioxocyclobuten-1,2-diyl or C=Z in which Z is ), 5, NCN, NNO2, CHNO2, NCONH2, C(CN)2, NCOR2, NCO2R2, NSO2R2, or NR3 in which R2 is (cl-6)alkYl or (C6-12)arYl and R3 is H or (Cl-6)alkyls B is (Cl-6)alkoXY, (Cl-6)alkYlthio or NR4R5 in whtch R4 and R5 are independently H, (Cl-l0)alkyl, C3-6(alkenyl), (C3-6)alkynyl, (C2-6)(primary hydroxy)alkyl, (C2-6)(primary amino) alkyl or (C3-6)cycloalkyl or R4 andR5 arejoined to form a 5- or 6-membered saturated ring optionally containing an additional O or NH: and the salts thereof. The compounds of the invention are histamine H-2 antagonists ana which lnhibit gastric acid secretion. |
priorityDate | 1978-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 145.