http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1120030-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ca2e4410855da087e11bf3eea8933fa |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-6555 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-655 |
filingDate | 1978-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1982-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f16c9db1f395ff3595114341f69f8ed5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c31d7d9136c9b21cf67a8a74a7a9f4a |
publicationDate | 1982-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-1120030-A |
titleOfInvention | Somatostatin analogs and intermediates thereto |
abstract | Abstract of the Disclosure The tetradecapeptide D-Val-Gly-L-Cys-L-Lys-L-Asn-L-Phe-L-Phe-D-Trp-L-Lys-L-Thr-L-Phe-L-Thr-L-Ser-L-Cys-OH is described along with its corresponding non-toxic pharmaceutically-acceptable acid addition salts as well as intermediates useful in the synthesis of this tetradecapeptide. This tetradecapeptide is prepared by reacting the corresponding straight-chain tetradecapeptide with an oxidizing agent to con-vert the two sulfhydryl groups to a disulfide bridge. This tetradecapeptide as well as its pharmaceutically acceptable acid addition salts exhibit various activities including inhibition of the release of growth hormone and reduction of gut motility. |
priorityDate | 1977-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 287.