| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ba090c867801ab7bccb082f1b694ad25 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D203-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-72 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-435
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D203-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D337-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-72 |
| filingDate |
1979-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1982-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46272f8fff9904defdef2781adfb365e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b47027c320dedcc996738089bfe5d53 |
| publicationDate |
1982-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-1118774-A |
| titleOfInvention |
Process for preparing nitro compounds |
| abstract |
ABSTRACT This invention concerns compounds showing activity as histamine H2-receptor antagonists. The compounds of the invention are of Structure where Het is a substituted or unsubstituted, fully-unsaturated 5- or 6- membered heterocycle containing at least one nitrogen atom, or a furan or thiophene ring substituded by a substituted or unsubstituted aminoalkyl group; Z is sulphur, methylene or oxygen; m is 0, 1 or 2, 3 is 2 or 3 with m + n being 3 or 4; and B is a substituted or unsubstituted alkanediyl group or a 2-substituted-2-aza-l,3-propanediyl group and acid addition salts thereof. The compounds of he invention can be prepared by reacting a compound of formula Het (CH2)mZ(CH2)nNH2 or Het(CH2)mY (where Y is a group dis-placeable by a mercaptan) with an appropriate 2-substituted-3-nitro-heterocycle. The compositions of the invention contain at least one compound of the inventicn and a pharma-ceutical carrier. |
| priorityDate |
1978-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |