http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1107736-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1bde28565d28f037e78bf4a67776ee24 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-62 |
| filingDate | 1978-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1981-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d78d3ddabdb946a7c177a529d8239992 |
| publicationDate | 1981-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-1107736-A |
| titleOfInvention | Heterocyclic compounds which are gaba-agonists and production of same |
| abstract | Abstract. The compound Ia Ia (4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridine-3-ol) has been shown to possess GABA-related activity. The invention relates to Ia and derivatives thereof, covered by the formula I VII in which R" is hydrogen, acetyl or a group of the general formula VII VII in which R5 is C1-8 alkyl; phenyl; phenyl substituted in the 4-position with halogen, lower alkoxy, or lower alkyl; or phenyl-alkyl in which the phenyl group may be substituted in the 4-posi-tion with halogen, lower alkoxy, or lower alkyl; and salts there-of. Novel intermediates for preparing I are - la - IV in which Alk is a lower alkyl group and Z is hydrogen or an amino-protecting group; VIII' wherein Z is hydrogen or an amino-protecting group, T is a group convertible, by hydrolysis, into an oxy group, and Q is a leaving group which, on reaction with hydroxylamine, forms a hydroxamic acid group; IX' wherein Z and T are as defined above; V wherein Z is as defined above, and W is hydrogen or a group removable to yield the free hydroxy group, with the proviso that at least one of Z and W is different from hydrogen. |
| priorityDate | 1977-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 177.