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filingDate 1979-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1981-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ca27707a4d38f252c04e9842301899d
publicationDate 1981-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-1106759-A
titleOfInvention Process for preparing a biological composition for use as a reference control in diagnostic analysis
abstract Abstract of the Disclosure A process for making a biological composition for use as a blood serum reference composition in diagnostic analysis. The process comprises: (a) adding calcium to citrated plasma and mixing well to form decitrated plasma; (b) adding thrombin to the decitrated plasma and mix-ing well to form a clot of fibrin; (c) performing at least one freeze-thaw routine on the clot to cause the fibrin to contract; (d) removing the fibrin to thereby obtain serum; (e) molecular washing and ultrafiltering the serum and thereby obtaining concentrated serum; and (f) adding to the concentrated serum at least one al-kylene polyol having from 2-5 carbon atoms in an amount such that said composition's non-biological component comprises from about 40 to about 85 weight percent water And from about 15 to about 60 weight percent of said alkylene polyol.
priorityDate 1978-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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