http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1104568-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4b8a28caa5561d6dbc92d613367b7ad2 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D223-16 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D223-16 |
filingDate | 1979-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1981-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73c6fca554d3a0119df6b5460ac97a07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59509ddf4bfd23e5ed04ec6f0637b561 |
publicationDate | 1981-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-1104568-A |
titleOfInvention | Preparation of 1,2,4,5-tetrahydro-7-alkoxy-(and 7,8- dialkoxy) - 3h, 3-benzazepines and 3-substituted derivatives thereof from the corresponding phenethylamines |
abstract | ABSTRACT Certain 1,2,4,5-tetrahydro-7-alkoxy-(and 7,8-dialkoxy)- 3H, 3-benzazepines are prepared in excellent yields by a three step process comprising reacting a 3-alkoxy-(or 3,4-dialkoxy)- phenethylamine with a halo-acetaldehyde dialkylacetal to form the corresponding N-(2,2-dialkoxyethyl) phenethylamine, reacting that product with BF3 to close the ring and to form a 1-alkoxy-1,2,3,4-tetrahydro-7-alkoxy-(or 7,8-dialkoxy)-3H, 3-benzazepine and reacting that product under reductive cleavage conditions to remove the 1-alkoxy group -ii-and to obtain the desired benzazepine. The benzazepines can be further reacted in the known manner or in the manner disclosed herein to form certain 3-substituted benzazepines. |
priorityDate | 1978-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 62.