http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1103161-A

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf8da2da8c87c78a55f5eb3608b95174
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2054
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-22
filingDate 1977-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1981-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_542d45848c11aea5f0d1e7f8f31243fc
publicationDate 1981-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-1103161-A
titleOfInvention Oral carrier base, its preparation and dosage units made therefrom
abstract ABSTRACT OF THE DISCLOSURE Shaped pharmaceutical tablets and other solid oral dosage unit forms which have a prolonged homogenous release pattern of active medicament over a period of hours wherein each shaped tablet or dosage unit comprises a carrier material base of hydroxypropylmethylcellulose with or without a proportion up to 20% of ethylcellulose and wherein the carrier material base is specially processed under controlled conditions of moisture, temperature and time, and then compressed at relatively low compression pressure with an incorporated active medicament. The compressed dosage units or tablets when orally administered give a continuous incremental release of the active medication without initial peaking and/or super or sub-therapeutic dosing. This provides effective blood levels free from any toxicity due to the carrier material which is chemically inert, of decreased solubility and enhanced stability, due to its processing and to the inclusion of a stabilizing agent.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8475841-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7919116-B2
priorityDate 1976-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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