http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1103161-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf8da2da8c87c78a55f5eb3608b95174 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2054 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-22 |
filingDate | 1977-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1981-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_542d45848c11aea5f0d1e7f8f31243fc |
publicationDate | 1981-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-1103161-A |
titleOfInvention | Oral carrier base, its preparation and dosage units made therefrom |
abstract | ABSTRACT OF THE DISCLOSURE Shaped pharmaceutical tablets and other solid oral dosage unit forms which have a prolonged homogenous release pattern of active medicament over a period of hours wherein each shaped tablet or dosage unit comprises a carrier material base of hydroxypropylmethylcellulose with or without a proportion up to 20% of ethylcellulose and wherein the carrier material base is specially processed under controlled conditions of moisture, temperature and time, and then compressed at relatively low compression pressure with an incorporated active medicament. The compressed dosage units or tablets when orally administered give a continuous incremental release of the active medication without initial peaking and/or super or sub-therapeutic dosing. This provides effective blood levels free from any toxicity due to the carrier material which is chemically inert, of decreased solubility and enhanced stability, due to its processing and to the inclusion of a stabilizing agent. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8475841-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7919116-B2 |
priorityDate | 1976-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 58.