http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1098530-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a157f5faa443ba5bb3367371f1e2a6c7 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-935 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-935 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-343 |
| filingDate | 1977-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1981-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f8d2bfa1d656e453cdebb354ec50fcce http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_348f418053d4fb8a8be0b29727c5301f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c039e54995208c452080be70ba10ab9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_705424bc9cc18f9be446a207e4aacc49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d0dcd30e7e597d1994e85ee729b0c3e9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf8ede25de21bba1c98b8dbe9c1e4c46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1609522374983f00c289842057b9a26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c889f531a94af0dd5bd24af7b8e4c1f0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_beb9724c748d03e15cc1dcd2a7344bef http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b98b38269c47014f32d3e0ff3db0eb4 |
| publicationDate | 1981-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-1098530-A |
| titleOfInvention | Process for the preparation of bicyclic enon compounds |
| abstract | ABSTRACT OF THE DISCLOSURE This invention relates to a process for the preparation of a racemic or optically active compound of the general formula V (V) wherein R stands for a hydrogen, acyl, alkyl or silyl, R1 and R2 together form an oxo group or R1 stands for a lower alkoxy, optionally substituted with one, two or three halogen atom(s) and R2 stands for a hydrogen, Q stands for a straight or branched chained alkyl having one to 10 carbon atoms, alkenyl containing one double bond or alkenyl containing one triple bond, which com-prises reacting a racemic or optically active lactone diol derivative of the general formula III (III) wherein R1 and R2 have the same meaning as defined above - with an oxidant, then further reacting the thus obtained aldehyde of the general formula II (II) wherein R1 and R2 have the same meaning as defined above - with a phosphorous compound of the general formula VI (VI) or VII (VII) wherein R3 stands for a lower alkyl and Q has the same meaning as defined above, preferably without separation, if desired, alkylating, acylating or silylating the hydroxyl of the obtained compounds of the general formula VIII (VIII) wherein R1, R2 and Q have the same meaning as defined above, and, if desired, preparing optically active compounds of the general formula V by the resolu-tion of a racemic compound of the general formula V. The compounds obtained are useful as starting materials for the preparation of prostaglandine inter-mediates of the formula (I) These intermediates are useful in the Corey prostaglandine synthesis in which prostaglandine derivatives are produced which have outstanding biological activity of the endogeneous tissue-hormones. |
| priorityDate | 1976-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 79.