| abstract |
ABSTRACT OF THE DISCLOSURE Novel isocyanates such as, for example, blocked L-tyrosine methyl ester isocyanate, are reacted with com-pounds of biological, clinical interest or the like such as, for example, digoxin, to form derivatives respective to tagging, as by radiolabeling The tagged derivatives may then be employed to determine the presence of a compound of interest in nanomolar or even picomolar amounts by using clinical analysis techniques such as radio-immunoassay. |