http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1089489-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_589e019870e8f74165d0734073a38d8e |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-12 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C237-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-00 |
filingDate | 1978-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1980-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_436c0953d61d1e857ff600afb71875cb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b43265bc9d83118b81581526ff0e15f |
publicationDate | 1980-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-1089489-A |
titleOfInvention | Water-soluble, non ionic radioopaque contrast agents (x-ray contrast agents) and process for their production |
abstract | ABSTRACT OF THE DISCLOSURE .alpha., .omega.-bis-[5-(dihydroxyalkyl) aminocarbonyl-3-hydroxyacyl-amino-2,4,6-triiodo-benzoyl-amino]-oxaalkane compounds of the formula wherein R1 is R and R' are hydrogen or methyl, R2 is dihydroxyalkyl having 3 or 4 carbon atoms n is 2 or 3, m is an integer between 1 and 5, and n(m+1) is an integer between 4 and 12, are readily soluble in water to yield injectable radio-paque contrast compositions which are well tolerated and stable. The compounds are prepared in good yields by reacting a reactive derivative of a 5-(di-hydroxyalkyl)-aminocarbonyl-3-acyloxyacylamino-2,4,6-triiodo-benzoic acid with an .alpha.,.omega.-diamino-oxaalkane of the formula R - NH - CnH2n- (O- CnH2n) - NH - R |
priorityDate | 1977-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 92.