http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1089359-A

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6115b7f4561db088f26a575e9339fed0
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-80
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-80
filingDate 1976-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1980-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2408d32c64068f32a05e65f579f13571
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e86fe80c40ce37afa64784c34fc9ad12
publicationDate 1980-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-1089359-A
titleOfInvention Blood cell typing and compatibility test by solid phase immunoadsorbtion
abstract ABSTRACT OF THE DISCLOSURE A solid-phase blood typing procedure is described based upon either agglutination or immune lysis. In this in-vention, a monolayer of ceils is irreversibly (e.g., covalently) bound to a solid matrix, and thereafter a serum containing antibodies is brought into contact with the bound cell layer. Immunoadsorption of antibodies by the bound cells occurs where the antigens of the cell membranes and the antibodies in the serum are complementary to each other. This antibody-sensitized monolayer of blood cells can either bind a second layer of blood cells carrying complementary antigen (solid-phase agglutination) or undergo lysis in the presence of serum complement (solid-phase immune lysis). Carrying out these reactions with a mono-layer of blood cells bound to a solid matrix allows quantitative evaluation of results by such standard instrumentable proce-dures as densitometric scanning, radioisotope counting, etc.
priorityDate 1975-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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