| abstract |
ABSTRACT OF THE DISCLOSURE Ibuprofen p-hydroxyphenylurea ester having the formula 11: was prepared from the free acid, ibuprofen [+2-(p-isobutyl-phenyl)propionic acid] (1). The ester 11 above has the anti-inflammatory activity of the free acid, but in contradistinction to it, it has a pleasant taste, suitable for oral administration such as uncoated tablets, suspensions or syrups, for the treatment of inflammatory conditions, particularly arthritis. |