abstract |
SPECIFIC New phenoxy derivatives of general formula I: I in which R and R ', identical or different, are hydrogen, halogen, alkyl, alkoxy or alkylthio from C1 to C5, nitro, amino, thifluoromethyl, trifluoromethylthio, trifluoro-methoxy, C2 to C6 alkoxycarbonyl, or dimethylsulfamoyl, and their addition salts with compatible acids, are prepared by reaction of a phenoxyaniline of formula II: II with a bis - (. beta.-haloethyl) amine of formula III: III in which X is halogen, then alkalinization of the hydrochloride thus formed. The new derivatives of formula I and their salts physiologically tolerable are used in therapy especially in the treatment of metabolic disorders of fats and carbohydrates. |