http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1084507-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f88f84fc279fe5d0b9b5ec3c88c2e2b2 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C43-20 |
| filingDate | 1978-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1980-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af4e290ef048c35d95b4813b1496ff93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c73e539c03ced83be413fc56b500f34 |
| publicationDate | 1980-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-1084507-A |
| titleOfInvention | 1-aryloxy-4-amino-2-butanols |
| abstract | ABSTRACT OF THE DISCLOSURE The present invention provides for preparing a compound of the formula ArO-CH2-CH2-CH-CH2-CH2-X (II) wherein Ar is selected from the group consisting of 1-naphthyl, 2-naphthyl, 3-(or 5-)chloro-2-pyridyl, inden-4-(or 5-)ly, phenyl, monosubstituted phenyl or disubstituted phenyl and X represents a halogen chosen from chlorine, bromine or iodine which comprises reacting together compounds of the formula ArOH and XCH2-CHOH-CH2-CH2-X wherein Ar and X are as defined above. Such compounds are novel intermediates useful in the preparation of pharmaceuticals of the formula ArO-CH2-CHOH-CH2-CH2-NR1R2 Formula I wherein; Ar is 1-naphthyl, 2-naphthyl, indene-4(or 5-)yl, 3-(or 5-) chloro-2 pyridyl, phenyl, monosubstituted phenyl or disubstituted phenyl, R1 is lower alkyl, phenyl, phenylalkyl, 2-hydroxymethyl-2-propyl, adamantyl or lower cycloalkyl, R2 is hydrogen or lower alkyl, R1 and R2 together with the ad-jacent nitrogen form a heterocyclic residue. |
| priorityDate | 1974-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 126.