| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-49
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-61
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-66
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-145
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-61
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-66
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-145
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06K9-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-49
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-48 |
| filingDate |
1978-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1980-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c59c4f75d56586f14ff4e1655ea61113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56b28685822e5242bfabf27c7a7081ba |
| publicationDate |
1980-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-1084498-A |
| titleOfInvention |
Benzylpyrimidines and process for the preparation thereof |
| abstract |
Abstract A process for the manufacture of benzylpyrimidines of the general formula (I) wherein R1 and R2 each represent a c1-6-alkyl group, R3 represents a C1-3-alkyl group and R4 represents the methylene group or a C2-4-aklylidene group, and of physiologically compatible acid addition salts thereof. The compounds of formula I have antibacterial activity. They inhibit the bacterial dihdrofolic acid reductase (DHFR) and, moreover, potentiate the activity of sulphonamides and other dihdrofolic acid synthetase inhibitors. |
| priorityDate |
1977-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |