| abstract |
PRECISION OF DISCLOSURE The invention relates to a method for obtaining N-acyl anines which correspond to the general formula 1: where n is an integer varying from 0 to 3; - R represents hydrogen or an alkyl radical inferior; - R1 represents a lower alkyl radical, a lower alkenyl radical, a lower alkyl phenyl radical or a lower cycloalkyl radical; - R2 is a radical of electrophilic nature chosen in the group consisting of a cyano radical, a radical trifluoromethyl and a lower alkanoyl radical; - R3 represents hydrogen or an alkyl radical inferior; - R4 represents hydrogen or an alkyl radical inferior; - X and Y, identical or different from each other. each represent a lower alkyl radical or form together an alkylene chain possibly interrupted by one or two heteroatoms, having 2 to 6 links, or X and R3 together form an alkylene chain having 2 to 4 carbon atoms, possibly interrupted by one or two additional heteroatoms, and their salts with a mineral or organic acid. The compounds of general formula I have properties interesting pharmacologicals which make them suitable for use medication, especially as an anti-ulcer medication. |