| abstract |
ABSTRACT OF THE DISCLOSURE The present invention is concerned with 1-(3,3,3-triarylpropyl)-4-phenyl-4-piperidinemethanols. These compounds are prepared by reacting the appropriate piperidine esters or piperidine ester-amideswith a suitable hydride reducing agent in an organic solvent to give the compounds of the instant invention. The compounds of the instant invention possess potent anti-diarrheal utility as evidenced by their ability to inhibit gastro-lntestinal motility. These subject compounds also possess a very low degree of analgesia. |