http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1077938-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-185 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C333-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-185 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C325-00 |
| filingDate | 1977-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1980-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1334cef61f2908d3a448e4a1b4a1d3ba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b2d83e75a6fd7f85b74b15c1cf40a2f3 |
| publicationDate | 1980-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-1077938-A |
| titleOfInvention | Fatty acid derivatives |
| abstract | ABSTRACT OF THE DISCLOSURE This invention relates to novel compounds of the general formula (I) , wherein R1 and R2 each independently represent a hydrogen or halogen atom or a methyl, methoxy or p-chlorophenoxy group, at least one of R1 and R2 being other than hydrogen, Y represents a cyano group or a group of the formula in which R3 represents a hydroxy, lower alkoxy or hydroxy-(lower alkoxy) group or a group of the formula -N(R4)(R5) group in which R4 represents a hydrogen atom and R5 represents a cyclo-alkyl group containing up to 6 carbon atoms or R4 and R5 each independently represent a hydrogen atom or a lower alkyl group or R4 and R5 together with the nitrogen atom to which they are attached represent a piperidine or morpholine ring, A represents a methylene, ethylene, propylene or -OCH2CH2- group and n stands for an integer of from 2 to 10 inclusive, and salts of acids of formula I with bases. These compounds and salts have blood-fat lowering activity. They can be prepared by a process which comprises reacting a compounds of the general formula (II) , wherein R1, R2 and A have the significance given in claim 1 and M+ represents Na , K+ or NH4+, with a compound of the general formula X(CH2)nY (III) , wherein X represents a halogen atom and Y and n have the significance given above, or with an alkali metal salt of a halocarboxylic acid of the general formula X(CH2)nCOOH (IV) wherein X and n have the significance given earlier in this claim, or reacting an isothiocyanate of the general formula (V) , wherein R1, R2 and A have the significance given above, with a mercaptan of the general formula HS - (CH2)n - Y (VI) , wherein Y and n have the significance given above, and, if desired, saponifying an ester obtained or an amide obtained to an acid, re-esterifying an ester obtained, esterifying an acid obtained or converting same into a salt with a base, hydrolysing a nitrile obtained to an amide or dehydrating an amide obtained to a nitrile. |
| priorityDate | 1976-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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