| abstract |
ABSTRACT 7.beta.-Acylamino-7.alpha.-alkoxycephalosporins, which are useful antibacterial agents, are prepared by reacting a 7-acylaminocephalosporin with a halogenating agent to give the corresponding imino halide, reacting this imino halide with a base to give a keteneimine, reacting the keteneimine with a halogen to give an .alpha.-haloimino halide, reacting the .alpha.-haloimino halide with an alkali metal alkoxide, and finally either reacting the resulting compound with an acid or a halogen-substituted silane and treating the resulting compound with water, or hydrolysing the product of the reaction between the alkali metal alkoxide and the .alpha.-haloimino halide. |