| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_faf522b8b83eded745c73018576219ba |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-875
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-104
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-385 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-41
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-104
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P1-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07G11-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-195
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 |
| filingDate |
1976-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1979-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_43dd6280248329b5ef4e4a41e314a5c3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed15916613a680fffe7062cdd50762af
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c797df7c11c3c2f392c18949d26973e1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90d1939ba15041c605bf4eabdbc012db
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d3dee41976a4c6e20ce576d2af1b9d8 |
| publicationDate |
1979-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-1060797-A |
| titleOfInvention |
Isolation of original protein endotoxin from pseudomonas aeruginosa |
| abstract |
Abstract of the Disclosure A dissociant strain of Pseudomonas aeruginosa was inoculated in a fermenter and cultured at 37°C. A quantity of an autolyzing agent such as toluene or chloroform was added to the bacterial culture several hours after the stationary state has been reached, so that it could be autolyzed. A component (OEP) consist-ing mainly of protein, and a small amount of lipid and sugar was isolated from the culture filtrate and purified by physicochemical methods until it is homogeneous. Then, OEP thus obtained was processed by either pro-teolytic enzyme or reductant, or after the process by reductant further digested by proteolytic enzymes drived from animal, plant and microorganism thereby preparing the bacterial component of Pseudomonas aeruginosa, possessing extremely strong anti-tumor and interferon inducting activities. This component possesses a speci-fic preventive property against infection due to Pseum domonas aeruginosa and non-specific protective property against infections by Pseudomonas aeruginosa as well as the other bacterial strains. When immunized with the bacterial component of Pseudomonas aeruginosa men-tioned above, an excellent preventive activity against virus and invasion of tumor could be obtained, and this bacterial component could also prevent infections by a certain serotype strains of Pseudomonas aeruginosa. |
| priorityDate |
1975-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |